Saeed Ghani is a Pakistani Politician and a Trade unionist who is currently Provincial Minister of Sindh for Information, Labour & Human Resources Departments. He is member of the Pakistan Peoples Party & is presently the Party President for the Karachi Division.

He was elected as Chairman Union Council ,Chanesar Goth,District East, Karachi twice from 2001-2010. He was leader of opposition in City District Council Karachi from 2002-2010.

He remained member of the Senate of Pakistan from March 2012 to August 2017. He was Parliamentary leader of PPPP in Senate of Pakistan from 2015-2017.

He was elected to the Provincial Assembly of Sindh as candidate of PPP from Constituency PS-114 (Karachi-XXVI) in by-Polls held in July 2017.
He was re-elected to the Provincial Assembly of Sindh as a candidate of PPP from the Constituency PS-104 (Karachi East-VI) in the General Elections of 2018.

In August 2018, he was inducted into the Provincial Cabinet of Sindh & was sworn as Provincial Minister of Sindh for Local Government & Housing Town Planning with the additional Ministerial Portfolios of Public Health Engineering and Rural Development, and Human Settlement Departments.
On 5th August 2019, his Ministerial Portfolios were changed to Labour, Information and Archives Departments.

His Ministerial Portfolios were changed to Education ,Literacy ,Labour & Human Resources Departments on 3rd February 2020.
On 5th August 2021, his Portfolios were again changed to Information , Labour & Human Resources Departments and he holds these till date .